MTCO3P23

Across TCGA pan-cancer cohorts, MTCO3P23 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MTCO3P23 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MTCO3P23 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO3P23 expression acts as an unfavorable survival marker, although some lineages such as LIHC and ESCA show a favorable association.

THCA, UVM, and OV are the cancer types where MTCO3P23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	III,IV	0.155	0.750	<.001	75	view →
UVM	DFS	Tertile	All	0.336	0.762	.004	45	view →
OV	DFS	Tertile	IV	0.231	0.532	<.001	36	view →
UCS	DFS	Tertile	III,IV	0.086	0.443	.007	36	view →
UCEC	DFS	Tertile	All	0.312	0.674	.027	36	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	27	view →
ACC	DFS	Tertile	III,IV	0.312	0.573	.018	27	view →
BRCA	DFS	Tertile	All	0.360	0.540	.021	24	view →
LIHC	OS	Tertile	III,IV	0.687	0.284	.014	24	view →
ESCA	DFS	Tertile	III,IV	0.567	0.271	.001	21	view →
LUSC	OS	Tertile	II,III,IV	0.330	0.624	.029	21	view →
TGCT	DFS	Tertile	All	0.035	0.837	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MTCO3P23–THCA (DFS)

Open the THCA breakdown →