Across TCGA pan-cancer cohorts, MTCO3P16 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTCO3P16’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MTCO3P16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCO3P16 is over-expressed in tumor.
LUSC are the cancer types where MTCO3P16 tumor–normal differential expression is most reproducible.