MTCO3P11

Across TCGA pan-cancer cohorts, MTCO3P11 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MTCO3P11’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MTCO3P11 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO3P11 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, KIRC, and LUAD are the cancer types where MTCO3P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO3P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.130	<.001	4	view →
KIRC	All	All	+0.038	.016	2	view →
LUAD	Male	III,IV	−0.238	.020	1	view →
THCA	Female	III,IV	−0.055	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MTCO3P11–LUSC

Open the LUSC breakdown →