MTCO2P8

Across TCGA pan-cancer cohorts, MTCO2P8 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTCO2P8 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MTCO2P8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO2P8 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

MESO, HNSC, and BRCA are the cancer types where MTCO2P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.137	0.589	.004	108	view →
HNSC	DFS	Tertile	II,III,IV	0.447	0.689	.027	45	view →
BRCA	DFS	Tertile	IV	0.175	0.730	.005	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
ESCA	OS	Tertile	III,IV	0.792	0.492	.019	27	view →
THCA	OS	Tertile	All	0.240	0.931	.007	18	view →
LIHC	OS	Tertile	II,III,IV	0.348	0.654	.023	12	view →
STAD	DFS	Tertile	III,IV	0.423	0.612	.026	9	view →
PCPG	DFS	Tertile	All	0.715	0.938	.022	6	view →
UCEC	OS	Tertile	All	0.875	0.930	.014	6	view →
LAML	DFS	Median	All	0.457	0.681	.025	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTCO2P8–MESO (OS)

Open the MESO breakdown →