MTCO2P5

Across TCGA patient cohorts, MTCO2P5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,922 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTCO2P5-associated GO terms across cancer lineages are Positive regulation of peptidyl-tyrosine phosphorylation, Activation of innate immune response, and Response to alcohol. Each is linked with MTCO2P5 in more than 7 cancer types. Because this analysis shows association rather than direction, both MTCO2P5-to-partner and partner-to-MTCO2P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of peptidyl-tyrosine phosphorylation grouped by MTCO2P5-low versus MTCO2P5-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO2P5→partner) and Y-score (partner→MTCO2P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of peptidyl-tyrosine phosphorylation →	+0.052	+0.120	<.001	.001	3	8
STAD	Activation of innate immune response →	+0.074	+0.060	<.001	<.001	3	6
STAD	Response to alcohol →	+0.059	+0.055	<.001	<.001	3	6
SKCM	Regulation of macrophage activation →	+0.066	+0.005	<.001	.004	3	6
STAD	Positive regulation of canonical NF-kappaB signal transduction →	+0.085	+0.057	<.001	<.001	3	6
STAD	Tissue remodeling →	+0.069	+0.056	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,922 associations by consensus.

Positive regulation of peptidyl-tyrosine phosphorylation by MTCO2P5 expression — ESCA

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