MTCO2P23

Across TCGA pan-cancer cohorts, MTCO2P23 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MTCO2P23 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MTCO2P23 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO2P23 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

HNSC, BRCA, and COAD are the cancer types where MTCO2P23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.122	0.723	<.001	87	view →
BRCA	DFS	Tertile	III,IV	0.268	0.801	<.001	66	view →
COAD	OS	Tertile	II,III,IV	0.084	0.855	<.001	45	view →
KIRC	OS	Tertile	II,III,IV	0.200	0.565	.003	27	view →
SKCM	OS	Tertile	III,IV	0.162	0.702	<.001	27	view →
STAD	OS	Tertile	III,IV	0.300	0.553	.019	18	view →
LUSC	OS	Tertile	All	0.660	0.777	.047	9	view →
KIRP	DFS	Tertile	All	0.314	0.631	.029	6	view →
PRAD	DFS	Tertile	All	0.759	0.935	.037	6	view →
LUAD	DFS	Tertile	All	1.000	0.333	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MTCO2P23–HNSC (OS)

Open the HNSC breakdown →