MTCO2P22

Across TCGA patient cohorts, MTCO2P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,628 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible MTCO2P22-associated GO terms across cancer lineages are Oxidative phosphorylation, ATP synthesis coupled electron transport, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with MTCO2P22 in more than 19 cancer types. Because this analysis shows association rather than direction, both MTCO2P22-to-partner and partner-to-MTCO2P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative phosphorylation grouped by MTCO2P22-low versus MTCO2P22-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO2P22→partner) and Y-score (partner→MTCO2P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Oxidative phosphorylation →	+0.047	+0.799	<.001	<.001	3	20
ESCA	ATP synthesis coupled electron transport →	+0.052	+0.838	<.001	<.001	1	19
THYM	Multi-pass transmembrane protein insertion into ER membrane →	+0.037	+0.727	.002	.004	2	18
STAD	Respiratory electron transport chain →	+0.046	+0.756	<.001	<.001	3	16
STAD	Proton transmembrane transport →	+0.054	+0.888	<.001	<.001	3	16
ESCA	Mitochondrial electron transport, NADH to ubiquinone →	+0.052	+0.750	<.001	<.001	1	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,628 associations by consensus.

Oxidative phosphorylation by MTCO2P22 expression — STAD

Explore this box plot interactively →