MTCO2P21

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MTCO2P21 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MTCO2P21 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MTCO2P21 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO2P21 expression acts as an unfavorable survival marker.

MESO, GBM, and STAD are the cancer types where MTCO2P21 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSTertileAll0.0990.487<.00154view →
GBMDFSTertileAll0.0610.246<.00127view →
STADOSQuartileAll0.2890.572.00715view →
ESCAOSQuartileIV0.1590.549.04512view →
CHOLOSTertileII,III,IV0.2010.700.0369view →
THCADFSTertileIV0.4630.902.0229view →
ACCDFSTertileAll0.1210.633.0289view →
KIRPDFSTertileAll0.3540.683.0353view →
LIHCDFSTertileAll0.4130.569.0383view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MTCO2P21–MESO (DFS)

Kaplan–Meier survival curve for MTCO2P21 RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration