MTCO1P9

Across TCGA pan-cancer cohorts, MTCO1P9 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MTCO1P9’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MTCO1P9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCO1P9 is over-expressed in tumor, although a few such as PAAD and THCA show the opposite, repressed pattern.

KICH, PAAD, and BRCA are the cancer types where MTCO1P9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO1P9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.032	<.001	4	view →
PAAD	Female	All	−0.065	.049	2	view →
BRCA	All	III,IV	+0.008	.040	2	view →
THCA	All	IV	−0.032	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MTCO1P9–KICH

Open the KICH breakdown →