Across TCGA pan-cancer cohorts, MTCO1P7 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTCO1P7’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where MTCO1P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCO1P7 is over-expressed in tumor.
KICH are the cancer types where MTCO1P7 tumor–normal differential expression is most reproducible.