Across TCGA pan-cancer cohorts, MTCO1P51 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTCO1P51’s most consistent transcriptional readouts.
The strongest signal is observed in rectum adenocarcinoma (READ), where MTCO1P51 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO1P51 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.
READ and LUAD are the cancer types where MTCO1P51 tumor–normal differential expression is most reproducible.