Across TCGA pan-cancer cohorts, MTCO1P43 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTCO1P43’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where MTCO1P43 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCO1P43 is over-expressed in tumor.
STAD are the cancer types where MTCO1P43 tumor–normal differential expression is most reproducible.