Across TCGA pan-cancer cohorts, MTCO1P3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTCO1P3’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where MTCO1P3 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO1P3 is over-expressed in tumor, although a few such as PAAD and CHOL show the opposite, repressed pattern.

PAAD, BRCA, and KICH are the cancer types where MTCO1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Female	All	−0.455	.040	2	view →
BRCA	Female	II,III,IV	+0.079	.022	2	view →
KICH	All	All	+0.259	.025	1	view →
CHOL	All	All	−0.191	.027	1	view →
LIHC	Female	All	−0.127	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MTCO1P3 RNA expression & survival · all MTCO1P3 data types