Q-omics provides the consensus-scored MTCO1P19 profile across patient tissues and cancer cell-line models. MTCO1P19 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, MTCO1P19 is differentially expressed in 3, with the highest sampling consensus in COAD. Additionally, MTCO1P19 RNA expression shows 9,868 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight BLCA, COAD, and LSCC as cancer lineages where MTCO1P19 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO1P19 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO1P19 survival associations across molecular data types. MTCO1P19 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO1P19 RNA expression–survival associations across cancer types. High MTCO1P19 expression shows unfavorable associations in CHOL, KIRC and LGG, but favorable associations in BLCA, LUAD and LAML. The BLCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for MTCO1P19 RNA expression.
This table summarizes MTCO1P19 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO1P19. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO1P19 shows higher tumor expression in COAD, HNSC and KICH. The COAD box plot shows higher MTCO1P19 RNA expression in tumor versus normal tissue (log2 FC = +0.064, t-test p = .014).
This table shows molecular features associated with MTCO1P19 in patient tissues and cancer cell lines. In patient samples, MTCO1P19 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
