MTCO1P18

Across TCGA pan-cancer cohorts, MTCO1P18 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MTCO1P18 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MTCO1P18 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO1P18 expression acts as an unfavorable survival marker, although some lineages such as ACC and KIRP show a favorable association.

UCS, ACC, and CHOL are the cancer types where MTCO1P18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	III,IV	0.144	0.605	.008	72	view →
ACC	DFS	Tertile	All	0.749	0.313	<.001	57	view →
CHOL	DFS	Tertile	II,III,IV	0.092	0.447	.002	51	view →
KIRP	DFS	Median	All	0.945	0.814	.005	41	view →
UCEC	OS	Tertile	III,IV	0.294	0.642	.013	30	view →
SKCM	OS	Tertile	III,IV	0.875	0.639	.010	25	view →
DLBC	OS	Tertile	All	0.528	0.945	.010	21	view →
READ	OS	Tertile	III,IV	1.000	0.315	.011	12	view →
COAD	DFS	Tertile	III,IV	0.175	0.476	.022	9	view →
PAAD	DFS	Tertile	II,III,IV	0.466	0.229	.048	6	view →
UVM	OS	Tertile	III,IV	1.000	0.548	.039	6	view →
LGG	OS	Tertile	All	0.943	0.859	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MTCO1P18–UCS (OS)

Open the UCS breakdown →