MTCO1P1

Across TCGA patient cohorts, MTCO1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,918 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MTCO1P1-associated GO terms across cancer lineages are Macromolecule methylation, Methylation, and Positive regulation of chromosome organization. Each is linked with MTCO1P1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MTCO1P1-to-partner and partner-to-MTCO1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by MTCO1P1-low versus MTCO1P1-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO1P1→partner) and Y-score (partner→MTCO1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Macromolecule methylation →	+0.030	+0.006	<.001	<.001	3	9
THYM	Methylation →	+0.038	+0.026	.001	.006	2	9
LUSC	Positive regulation of chromosome organization →	+0.034	+0.026	<.001	<.001	3	7
KIRP	Negative regulation of mRNA metabolic process →	+0.031	+0.008	.001	.003	3	7
LUSC	Positive regulation of protein modification by small protein conjugation or removal →	+0.031	+0.029	<.001	<.001	3	7
LUSC	Regulation of telomere maintenance via telomere lengthening →	+0.032	+0.026	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,918 associations by consensus.

Macromolecule methylation by MTCO1P1 expression — HNSC

Explore this box plot interactively →