MTCH1

Across TCGA cell cohorts, MTCH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,319 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MTCH1-associated GO terms across cancer lineages are Regulation of anaphase-promoting complex-dependent catabolic process, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Cytoskeleton-dependent cytokinesis. Each is linked with MTCH1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MTCH1-to-partner and partner-to-MTCH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of anaphase-promoting complex-dependent catabolic process grouped by MTCH1-low versus MTCH1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCH1→partner) and Y-score (partner→MTCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.130	+0.897	<.001	<.001	3	17
CNS	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.112	+0.589	<.001	<.001	3	17
BREAST	Cytoskeleton-dependent cytokinesis →	+0.067	+1.037	.007	<.001	3	14
SKIN	Positive regulation of synaptic plasticity →	+0.141	+0.628	.001	<.001	3	13
LARGE_INTESTINE	Protein depolymerization →	+0.109	+0.659	<.001	<.001	3	13
OVARY	Regulation of Golgi inheritance →	+0.167	+0.698	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,319 associations by consensus.

Regulation of anaphase-promoting complex-dependent catabolic process by MTCH1 expression — BLOOD_Lymphoma

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