MTBP

Across TCGA patient cohorts, MTBP protein abundance is significantly associated with the RNA expression of many other genes, with 10,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MTBP-associated genes across cancer lineages are FOXM1, ABCC1, and ZNF670-ZNF695. Each is linked with MTBP in more than 2 cancer types. Because this analysis shows association rather than direction, both MTBP-to-partner and partner-to-MTBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTBP versus FOXM1 in HNSC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTBP→partner) and Y-score (partner→MTBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FOXM1 →	+1.623	+0.681	<.001	.004	3	3
HNSC	ABCC1 →	+1.304	+0.617	.005	.004	3	2
HNSC	ZNF670-ZNF695 →	+0.810	+0.508	.007	.008	2	3
HNSC	PTH2R →	+3.419	+0.758	.001	.006	3	2
HNSC	CCNF →	+1.051	+0.651	.003	.003	3	2
HNSC	ZNF695 →	+1.628	+0.557	.002	.006	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,360 associations by consensus.

MTBP vs FOXM1 — HNSC

Explore this scatter interactively →