MTBP

Across TCGA cell cohorts, MTBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,360 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MTBP-associated GO terms across cancer lineages are Replication fork processing, Protein localization to chromosome, and Sister chromatid cohesion. Each is linked with MTBP in more than 19 cancer types. Because this analysis shows association rather than direction, both MTBP-to-partner and partner-to-MTBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by MTBP-low versus MTBP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTBP→partner) and Y-score (partner→MTBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Replication fork processing →	+0.130	+1.360	.003	<.001	3	20
LUNG_SCLC	Protein localization to chromosome →	+0.121	+0.979	<.001	<.001	3	20
BONE	Sister chromatid cohesion →	+0.137	+1.327	.002	<.001	3	20
OESOPHAGUS	Resolution of DNA recombination intermediates →	+0.199	+1.053	<.001	.002	3	20
LUNG_NSCLC_LUSC	Recombinational repair →	+0.084	+1.591	<.001	<.001	3	20
BONE	Protein localization to condensed chromosome →	+0.212	+1.439	.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,360 associations by consensus.

Replication fork processing by MTBP expression — BONE

Explore this box plot interactively →