Across TCGA pan-cancer cohorts, MTATP8P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MTATP8P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MTATP8P1 RNA is repressed in tumor relative to normal tissue. In most cancer types MTATP8P1 is over-expressed in tumor, although a few such as KIRC and LIHC show the opposite, repressed pattern.
KIRC, KICH, and LIHC are the cancer types where MTATP8P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTATP8P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.