Across TCGA pan-cancer cohorts, MTATP6P14 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTATP6P14’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MTATP6P14 RNA is repressed in tumor relative to normal tissue. In most cancer types MTATP6P14 is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.
KIRC and LUSC are the cancer types where MTATP6P14 tumor–normal differential expression is most reproducible.