MTATP6P1

Across TCGA pan-cancer cohorts, MTATP6P1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MTATP6P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MTATP6P1 RNA is repressed in tumor relative to normal tissue. In most cancer types MTATP6P1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and BRCA are the cancer types where MTATP6P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTATP6P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	−0.930	<.001	9	view →
KIRP	All	II,III,IV	−1.098	.001	8	view →
BRCA	All	All	−0.543	<.001	6	view →
KICH	Female	II,III,IV	+1.658	<.001	4	view →
CHOL	All	All	−0.617	.009	4	view →
LIHC	Female	II,III,IV	−0.721	.003	3	view →
READ	Female	All	+1.006	.004	2	view →
HNSC	Female	IV	−0.995	.019	2	view →
LUSC	Male	All	−0.490	.002	2	view →
PRAD	All	All	+0.372	.009	2	view →
THCA	Male	III,IV	+0.570	.020	1	view →
LUAD	All	All	−0.549	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MTATP6P1–KIRC

Open the KIRC breakdown →