MTARC2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MTARC2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MTARC2-associated genes across cancer lineages are GP9, TCP10L3, and OR2M5. Each is linked with MTARC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTARC2-to-partner and partner-to-MTARC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP9 grouped by MTARC2-low versus MTARC2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTARC2→partner) and Y-score (partner→MTARC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaGP9 →+0.421+4.867<.001.00931
BLOOD_LymphomaTCP10L3 →+0.059+4.867<.001.00931
LARGE_INTESTINEOR2M5 →+0.016+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GP9 by MTARC2 expression — BLOOD_Lymphoma

Box plot of GP9 in MTARC2-low vs MTARC2-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration