Across TCGA pan-cancer cohorts, MTARC1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MTARC1 data layer compared with 21 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MTARC1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MTARC1 expression acts as an unfavorable survival marker.

HNSC, PDAC, and UCEC are the cancer types where MTARC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.788	0.927	.009	30	view →
PDAC	OS	Tertile	II,III,IV	0.398	0.769	.002	22	view →
UCEC	DFS	Median	All	0.935	1.000	.019	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MTARC1 tumor-vs-normal RNA expression · all MTARC1 data types