MTA2

Across TCGA patient cohorts, MTA2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,427 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MTA2-associated genes across cancer lineages are LIN9, NCAPH, and RRP15. Each is linked with MTA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MTA2-to-partner and partner-to-MTA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTA2 versus LIN9 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTA2→partner) and Y-score (partner→MTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIN9 →	+0.660	+0.204	<.001	<.001	3	7
BRCA	NCAPH →	+1.010	+0.418	<.001	<.001	3	6
UCEC	RRP15 →	+0.509	+0.265	<.001	<.001	3	6
BRCA	BIRC5 →	+1.155	+0.230	<.001	<.001	3	6
HNSC	TMPO →	+0.930	+0.261	<.001	<.001	3	6
GBM	SGO1 →	+0.686	+0.332	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,427 associations by consensus.

MTA2 vs LIN9 — LSCC

Explore this scatter interactively →