Across TCGA patient cohorts, MTA1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,659 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTA1-associated genes across cancer lineages are VRK1, CDCA4, and SNHG10. Each is linked with MTA1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MTA1-to-partner and partner-to-MTA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTA1→partner) and Y-score (partner→MTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VRK1 →	+0.914	+0.313	<.001	<.001	3	9
LSCC	CDCA4 →	+0.983	+0.505	<.001	<.001	3	9
OV	SNHG10 →	+0.599	+0.390	<.001	<.001	3	9
HNSC	ALKBH1 →	+0.534	+0.309	.001	<.001	3	8
HNSC	EIF5 →	+0.910	+0.394	.002	<.001	3	8
HNSC	ZC3H14 →	+0.645	+0.455	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,659 associations by consensus.

Exploration

MTA1 survival (RNA) · tumor vs normal (RNA) · all MTA1 data types