Across TCGA patient cohorts, MTA1 mutation is significantly associated with the RNA expression of many other genes, with 2,513 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTA1-associated genes across cancer lineages are MRPL16, ITGAE, and RTRAF. Each is linked with MTA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MTA1-to-partner and partner-to-MTA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTA1→partner) and Y-score (partner→MTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRPL16 →	+0.551	+3.469	<.001	.002	3	3
COAD	ITGAE →	+0.610	+3.183	<.001	.009	3	3
COAD	RTRAF →	+0.475	+3.210	.001	.009	3	3
UCEC	TIPIN →	+0.564	+3.080	<.001	<.001	3	3
UCEC	NOP10 →	+0.349	+2.560	.003	<.001	3	3
UCEC	PSME2P1 →	+0.541	+2.695	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,513 associations by consensus.

Exploration

MTA1 survival (RNA) · tumor vs normal (RNA) · all MTA1 data types