Across TCGA cell cohorts, MTA1 mutation is significantly associated with the mutation status of many other genes, with 5,713 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTA1-associated genes across cancer lineages are BICRA, TCERG1, and CACNA2D4. Each is linked with MTA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTA1-to-partner and partner-to-MTA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTA1→partner) and Y-score (partner→MTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	BICRA →	+3.169	+4.548	.004	.004	1	6
BREAST	TCERG1 →	+4.857	+4.297	.009	.009	1	5
BREAST	CACNA2D4 →	+4.857	+4.297	.009	.009	1	5
CNS	WDR33 →	+5.277	+4.459	.005	.005	1	5
OVARY	EMSY →	+4.977	+4.415	.007	.007	1	5
LARGE_INTESTINE	ARHGEF12 →	+2.807	+3.321	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,713 associations by consensus.

Exploration

MTA1 survival (RNA) · tumor vs normal (RNA) · all MTA1 data types