MT2A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MT2A mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible MT2A-associated genes across cancer lineages are Astrocytes. Each is linked with MT2A in more than 1 cancer types. Because this analysis shows association rather than direction, both MT2A-to-partner and partner-to-MT2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by MT2A-low versus MT2A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT2A→partner) and Y-score (partner→MT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCAstrocytes →+0.164+5.479<.001.04331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Astrocytes by MT2A expression — LIHC

Box plot of Astrocytes in MT2A-low vs MT2A-high samples in LIHC.

Explore this box plot interactively →

Exploration