Across TCGA patient cohorts, MT1X protein abundance is significantly associated with the RNA expression of many other genes, with 7,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MT1X-associated genes across cancer lineages are MT2A, MT1E, and TMEM45A. Each is linked with MT1X in more than 6 cancer types. Because this analysis shows association rather than direction, both MT1X-to-partner and partner-to-MT1X results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT1X→partner) and Y-score (partner→MT1X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MT2A →	+1.182	+0.596	<.001	<.001	3	7
UCEC	MT1E →	+2.114	+0.601	<.001	<.001	3	5
LUAD	TMEM45A →	+0.936	+0.912	<.001	<.001	3	5
LSCC	AHNAK2 →	+1.340	+0.845	<.001	<.001	3	5
UCEC	MT1F →	+1.333	+0.953	<.001	<.001	3	4
BRCA	CLEC2B →	+0.580	+0.650	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,886 associations by consensus.

Exploration

MT1X survival (RNA) · tumor vs normal (RNA) · all MT1X data types