MT1JP

Across TCGA pan-cancer cohorts, MT1JP RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of MT1JP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MT1JP RNA is repressed in tumor relative to normal tissue. In most cancer types MT1JP is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.

COAD, LUAD, and LIHC are the cancer types where MT1JP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MT1JP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−0.658	<.001	11	view →
LUAD	All	III,IV	−1.050	<.001	9	view →
LIHC	All	All	−0.840	<.001	9	view →
KICH	All	II,III,IV	−0.486	<.001	9	view →
KIRP	Male	All	−0.361	<.001	9	view →
BRCA	All	II,III,IV	−0.429	<.001	8	view →
BLCA	All	All	−0.535	.003	7	view →
HNSC	Male	All	−0.175	.004	7	view →
LUSC	Male	II,III,IV	−1.381	<.001	6	view →
STAD	All	All	−0.453	.001	5	view →
KIRC	Male	All	−0.122	<.001	5	view →
READ	All	III,IV	−0.975	.007	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

MT1JP–COAD

Open the COAD breakdown →