Across TCGA pan-cancer cohorts, MT1H mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MT1H data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MT1H mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MT1H expression acts as an unfavorable survival marker.

CCRCC are the cancer types where MT1H mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	0.291	0.981	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: MT1H tumor-vs-normal RNA expression · all MT1H data types