MT1G

Across TCGA pan-cancer cohorts, MT1G Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MT1G data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MT1G Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MT1G expression acts as an unfavorable survival marker.

COAD, LUSC, and KIRP are the cancer types where MT1G Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.111	0.871	<.001	22	view →
LUSC	OS	Median	All	0.537	0.776	<.001	20	view →
KIRP	DFS	Median	All	0.277	0.867	.004	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MT1G–COAD (OS)

Open the COAD breakdown →