MT1E

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MT1E mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MT1E-associated genes across cancer lineages are NK cells and Adipocytes. Each is linked with MT1E in more than 1 cancer types. Because this analysis shows association rather than direction, both MT1E-to-partner and partner-to-MT1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by MT1E-low versus MT1E-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT1E→partner) and Y-score (partner→MT1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNK cells →+0.004+5.597.004.04031
UCECAdipocytes →+0.042+2.729<.001.00931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NK cells by MT1E expression — STAD

Box plot of NK cells in MT1E-low vs MT1E-high samples in STAD.

Explore this box plot interactively →

Exploration