Across TCGA patient cohorts, MT-TD RNA expression is significantly associated with the go_rna of many other GO terms, with 2,493 significant associations in total. LAML shows the largest number of these associations.

The most reproducible MT-TD-associated GO terms across cancer lineages are Positive regulation of dopaminergic neuron differentiation, Mitochondrial ATP transmembrane transport, and Obsolete histone H2A acetylation. Each is linked with MT-TD in more than 2 cancer types. Because this analysis shows association rather than direction, both MT-TD-to-partner and partner-to-MT-TD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TD→partner) and Y-score (partner→MT-TD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Positive regulation of dopaminergic neuron differentiation →	-0.086	-1.257	<.001	<.001	3	3
HNSC	Mitochondrial ATP transmembrane transport →	+0.081	+0.055	<.001	.002	3	3
LAML	Obsolete histone H2A acetylation →	-0.055	-1.106	<.001	<.001	3	3
LAML	Cytoplasmic sequestering of protein →	-0.037	-0.879	<.001	<.001	3	3
LAML	Renal protein absorption →	-0.071	-0.838	<.001	<.001	3	3
ACC	Protein repair →	+0.079	+0.308	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,493 associations by consensus.

Exploration

MT-TD survival (RNA) · tumor vs normal (RNA) · all MT-TD data types