Across TCGA patient cohorts, MT-ND5 protein abundance is significantly associated with the RNA expression of many other genes, with 5,181 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MT-ND5-associated genes across cancer lineages are PDLIM7, CTSF, and VIM. Each is linked with MT-ND5 in more than 2 cancer types. Because this analysis shows association rather than direction, both MT-ND5-to-partner and partner-to-MT-ND5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND5→partner) and Y-score (partner→MT-ND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDLIM7 →	-0.641	-0.504	<.001	<.001	3	3
OV	CTSF →	+0.986	+0.350	<.001	.003	3	3
OV	VIM →	-0.718	-0.329	.007	.005	3	3
COAD	CARMIL2 →	+0.358	+0.227	<.001	.006	3	3
GBM	NAP1L2 →	+0.972	+0.301	<.001	<.001	3	3
UCEC	PLEKHA4 →	-1.108	-0.444	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,181 associations by consensus.

Exploration

MT-ND5 survival (RNA) · tumor vs normal (RNA) · all MT-ND5 data types