Across TCGA cell cohorts, MT-ND5 mutation is significantly associated with the RNA expression of many other genes, with 1,944 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MT-ND5-associated genes across cancer lineages are ARR3, MYO9B, and TPM3. Each is linked with MT-ND5 in more than 5 cancer types. Because this analysis shows association rather than direction, both MT-ND5-to-partner and partner-to-MT-ND5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND5→partner) and Y-score (partner→MT-ND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ARR3 →	+0.153	+2.310	.001	.006	3	5
CNS	MYO9B →	+0.573	+3.529	.001	<.001	3	5
OVARY	TPM3 →	+0.622	+3.074	.005	.008	2	6
PANCREAS	ELP1 →	+0.715	+3.378	.007	.002	2	5
CNS	RAB5C →	+0.431	+2.167	.006	.002	3	4
BLOOD_Leukemia	KIAA2013 →	+0.282	+2.058	.004	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,944 associations by consensus.

Exploration

MT-ND5 survival (RNA) · tumor vs normal (RNA) · all MT-ND5 data types