MT-ND4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MT-ND4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,149 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MT-ND4-associated GO terms across cancer lineages are Negative regulation of ubiquitin protein ligase activity, Swimming behavior, and tRNA wobble cytosine modification. Each is linked with MT-ND4 in more than 9 cancer types. Because this analysis shows association rather than direction, both MT-ND4-to-partner and partner-to-MT-ND4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND4→partner) and Y-score (partner→MT-ND4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTNegative regulation of ubiquitin protein ligase activity →-0.199-1.018.002.005310
LUNG_NSCLC_LUADSwimming behavior →-0.113-0.834<.001<.00139
UPPER_AERODIGESTIVE_TRACTtRNA wobble cytosine modification →-0.072-1.690.001<.00139
OVARYMaintenance of unfolded protein →+0.135+1.060<.001<.00139
PANCREASRegulation of pigment cell differentiation →-0.145-0.769.002.00629
PANCREASPositive regulation of pigment cell differentiation →-0.145-0.769.002.00629
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,149 associations by consensus.

Exploration