Across TCGA patient cohorts, MT-ATP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,259 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MT-ATP8-associated proteins across cancer lineages are MRPL43, MRPL11, and MRPL23. Each is linked with MT-ATP8 in more than 4 cancer types. Because this analysis shows association rather than direction, both MT-ATP8-to-partner and partner-to-MT-ATP8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ATP8→partner) and Y-score (partner→MT-ATP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MRPL43 →	+0.444	+0.825	.002	.001	3	5
PDAC	MRPL11 →	+0.426	+1.007	<.001	<.001	3	4
PDAC	MRPL23 →	+0.763	+1.136	<.001	<.001	3	4
COAD	MRPL49 →	+0.397	+0.707	.001	.004	3	4
COAD	SLIRP →	+0.466	+0.790	<.001	.003	3	4
LSCC	DAP3 →	+0.318	+0.678	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,259 associations by consensus.

Exploration

MT-ATP8 survival (RNA) · tumor vs normal (RNA) · all MT-ATP8 data types