MSX1

Across TCGA patient cohorts, MSX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,813 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MSX1-associated proteins across cancer lineages are PCOLCE, ARFGEF2, and NID2. Each is linked with MSX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MSX1-to-partner and partner-to-MSX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSX1 versus PCOLCE in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MSX1→partner) and Y-score (partner→MSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PCOLCE →	+0.681	+0.750	<.001	<.001	3	4
CCRCC	ARFGEF2 →	-0.251	-0.595	<.001	<.001	3	4
BRCA	NID2 →	+0.402	+0.518	<.001	.004	3	4
CCRCC	PEAK1 →	+0.279	+0.504	<.001	<.001	3	4
CCRCC	C6 →	+0.662	+0.551	<.001	<.001	3	4
PDAC	ASPN →	+0.973	+0.502	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,813 associations by consensus.

MSX1 vs PCOLCE — BRCA

Explore this scatter interactively →