MST1

Across TCGA patient cohorts, MST1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,250 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MST1-associated genes across cancer lineages are MSRB3, VEGFC, and COL15A1. Each is linked with MST1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MST1-to-partner and partner-to-MST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MST1 versus MSRB3 in COAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MST1→partner) and Y-score (partner→MST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MSRB3 →	+1.297	+0.666	<.001	<.001	3	9
LSCC	VEGFC →	+0.990	+0.546	<.001	<.001	3	8
COAD	COL15A1 →	+1.283	+0.445	<.001	.001	3	8
OV	ISLR →	+1.224	+0.568	.001	.001	3	8
COAD	AOC3 →	+1.430	+0.570	<.001	<.001	3	8
BRCA	MEIS3 →	+1.197	+0.499	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,250 associations by consensus.

MST1 vs MSRB3 — COAD

Explore this scatter interactively →