MSS51

Across TCGA cell cohorts, MSS51 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,831 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MSS51-associated GO terms across cancer lineages are mRNA splice site recognition, Regulation of sister chromatid cohesion, and Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with MSS51 in more than 13 cancer types. Because this analysis shows association rather than direction, both MSS51-to-partner and partner-to-MSS51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by MSS51-low versus MSS51-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSS51→partner) and Y-score (partner→MSS51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.128	+0.536	<.001	<.001	3	14
BONE	Regulation of sister chromatid cohesion →	+0.115	+0.636	.001	.001	3	13
URINARY_TRACT	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.114	+0.625	<.001	.001	3	12
BONE	Subtelomeric heterochromatin formation →	+0.152	+0.722	<.001	<.001	3	12
BONE	Chiasma assembly →	+0.449	+0.673	.008	<.001	3	11
BONE	Microtubule nucleation →	+0.144	+0.692	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,831 associations by consensus.

mRNA splice site recognition by MSS51 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →