MSRB3

Across TCGA patient cohorts, MSRB3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,317 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MSRB3-associated genes across cancer lineages are MYL9, ACTA2, and ISLR. Each is linked with MSRB3 in more than 9 cancer types. Because this analysis shows association rather than direction, both MSRB3-to-partner and partner-to-MSRB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSRB3 versus MYL9 in UCEC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB3→partner) and Y-score (partner→MSRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.408	+0.797	<.001	<.001	3	10
UCEC	ACTA2 →	+1.692	+0.941	<.001	<.001	3	10
CCRCC	ISLR →	+1.670	+0.582	<.001	<.001	3	10
UCEC	CNN1 →	+2.548	+1.068	<.001	<.001	3	10
BRCA	AOC3 →	+1.531	+0.943	<.001	<.001	3	10
BRCA	FGF7 →	+1.423	+0.839	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,317 associations by consensus.

MSRB3 vs MYL9 — UCEC

Explore this scatter interactively →