MSRB3

Across TCGA cell cohorts, MSRB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,133 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MSRB3-associated GO terms across cancer lineages are Keratinocyte development, Regulation of hippo signaling, and Establishment of epithelial cell apical/basal polarity. Each is linked with MSRB3 in more than 11 cancer types. Because this analysis shows association rather than direction, both MSRB3-to-partner and partner-to-MSRB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte development grouped by MSRB3-low versus MSRB3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB3→partner) and Y-score (partner→MSRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Keratinocyte development →	+0.480	+2.508	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of hippo signaling →	+0.071	+1.118	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.216	+2.379	<.001	<.001	3	12
OVARY	Foam cell differentiation →	+0.224	+1.874	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Action potential propagation →	+1.115	+2.373	<.001	<.001	3	12
STOMACH	Vesicle cargo loading →	+0.115	+2.036	.004	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,133 associations by consensus.

Keratinocyte development by MSRB3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →