MSRB2

Across TCGA patient cohorts, MSRB2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,351 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MSRB2-associated genes across cancer lineages are TTK, NCAPH, and PIMREG. Each is linked with MSRB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MSRB2-to-partner and partner-to-MSRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSRB2 versus TTK in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB2→partner) and Y-score (partner→MSRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TTK →	-0.873	-0.353	.001	.001	3	5
UCEC	NCAPH →	-0.929	-0.459	<.001	<.001	3	5
GBM	PIMREG →	-1.165	-0.417	.001	.001	3	5
GBM	BRIP1 →	-1.043	-0.490	<.001	<.001	3	5
UCEC	KIF23 →	-0.970	-0.431	<.001	<.001	3	5
UCEC	KIF11 →	-0.764	-0.392	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,351 associations by consensus.

MSRB2 vs TTK — UCEC

Explore this scatter interactively →