Across TCGA patient cohorts, MSRB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,536 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MSRB1-associated proteins across cancer lineages are FPGS, JPT2, and PARP4. Each is linked with MSRB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MSRB1-to-partner and partner-to-MSRB1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB1→partner) and Y-score (partner→MSRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FPGS →	+0.322	+0.817	<.001	<.001	3	5
UCEC	JPT2 →	+0.394	+0.929	<.001	<.001	2	6
GBM	PARP4 →	+0.375	+0.242	.003	.003	3	5
UCEC	TOP2B →	-0.291	-0.884	<.001	<.001	3	4
LSCC	ARL3 →	-0.281	-0.581	.001	<.001	3	4
CCRCC	SSC5D →	-0.612	-0.518	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,536 associations by consensus.

Exploration

MSRB1 survival (RNA) · tumor vs normal (RNA) · all MSRB1 data types