Across TCGA patient cohorts, MSRB1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,992 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MSRB1-associated genes across cancer lineages are HSPA9, CCNB1, and S100A8. Each is linked with MSRB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MSRB1-to-partner and partner-to-MSRB1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB1→partner) and Y-score (partner→MSRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HSPA9 →	+0.366	+0.366	<.001	<.001	3	3
UCEC	CCNB1 →	+1.708	+0.978	.004	.005	3	3
PDAC	S100A8 →	+1.450	+0.908	<.001	.001	3	3
PDAC	SLC25A37 →	+0.809	+0.779	.001	.007	3	3
PDAC	S100A9 →	+1.571	+0.924	.001	.001	3	3
PDAC	SVEP1 →	-1.454	-0.974	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,992 associations by consensus.

Exploration

MSRB1 survival (RNA) · tumor vs normal (RNA) · all MSRB1 data types