Across TCGA cell cohorts, MSRB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,447 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MSRB1-associated GO terms across cancer lineages are Negative regulation of release of cytochrome c from mitochondria, Protein repair, and N-terminal protein amino acid acetylation. Each is linked with MSRB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MSRB1-to-partner and partner-to-MSRB1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB1→partner) and Y-score (partner→MSRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of release of cytochrome c from mitochondria →	+0.140	+0.767	.004	.008	3	10
BREAST	Protein repair →	+0.170	+0.858	<.001	<.001	3	9
LUNG_SCLC	N-terminal protein amino acid acetylation →	+0.185	+1.181	<.001	<.001	3	9
LUNG_SCLC	Arp2/3 complex-mediated actin nucleation →	+0.160	+1.446	<.001	<.001	3	8
BONE	Lysosome organization →	+0.063	+0.969	<.001	<.001	3	8
BONE	Lytic vacuole organization →	+0.063	+0.969	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,447 associations by consensus.

Exploration

MSRB1 survival (RNA) · tumor vs normal (RNA) · all MSRB1 data types