MSL3

Across TCGA cell cohorts, MSL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,465 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MSL3-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Centriole-centriole cohesion, and Negative regulation of cell cycle phase transition. Each is linked with MSL3 in more than 11 cancer types. Because this analysis shows association rather than direction, both MSL3-to-partner and partner-to-MSL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by MSL3-low versus MSL3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSL3→partner) and Y-score (partner→MSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of cell cycle process →	+0.062	+0.818	<.001	.001	3	12
LUNG_SCLC	Centriole-centriole cohesion →	+0.109	+0.727	<.001	<.001	3	11
BLOOD_Myeloma	Negative regulation of cell cycle phase transition →	+0.055	+0.944	.007	.004	3	11
LUNG_SCLC	Positive regulation of pinocytosis →	+0.101	+0.645	.002	.001	3	10
BLOOD_Myeloma	Microtubule cytoskeleton organization involved in mitosis →	+0.106	+0.931	<.001	<.001	3	10
LIVER	Negative regulation of organelle assembly →	+0.066	+1.186	.004	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,465 associations by consensus.

Negative regulation of cell cycle process by MSL3 expression — BLOOD_Myeloma

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