MSL2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MSL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,958 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MSL2-associated proteins across cancer lineages are SMC1A, GATAD2B, and HCFC1. Each is linked with MSL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both MSL2-to-partner and partner-to-MSL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSL2 versus SMC1A in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MSL2→partner) and Y-score (partner→MSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSMC1A →+0.234+0.221<.001<.00139
GBMGATAD2B →+0.314+0.372<.001<.00138
PDACHCFC1 →+0.221+0.364<.001<.00138
LSCCHMCES →+0.640+0.719<.001<.00138
GBMPRPF4 →+0.334+0.345<.001<.00137
GBMACIN1 →+0.356+0.324<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,958 associations by consensus.

MSL2 vs SMC1A — GBM

Per-sample scatter of MSL2 vs SMC1A in GBM (Pearson r = 0.54).

Explore this scatter interactively →

Exploration